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Fwd: PLoS ONE New Articles Published

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From: "PLoS ONE" <news@lists.plos.org>
Date: Dec 8, 2011 7:00 PM
Subject: PLoS ONE New Articles Published
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New Articles in PLoS ONE

Published December 01, 2011 to December 07, 2011

If articles are interdisciplinary then they may appear under more than one subject heading in the list below.

Subjects:

Anesthesiology and Pain Management

IL-4 Deficiency Is Associated with Mechanical Hypersensitivity in Mice
Nurcan Üçeyler, Tengü Topuzoğlu, Peter Schießer, Saskia Hahnenkamp, Claudia Sommer

Propofol Inhibits the Activation of p38 through Up-Regulating the Expression of Annexin A1 to Exert Its Anti-Inflammation Effect
Jing Tang, Xi Chen, Weifeng Tu, Yuanbo Guo, Zhenlong Zhao, Qiong Xue, Chunshui Lin, Jinfang Xiao, Xuegang Sun, Tao Tao, Miaoning Gu, Youtan Liu

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Biochemistry

Modulation of Calcium-Dependent Inactivation of L-Type Ca2+ Channels via β-Adrenergic Signaling in Thalamocortical Relay Neurons
Vladan Rankovic, Peter Landgraf, Tatyana Kanyshkova, Petra Ehling, Sven G. Meuth, Michael R. Kreutz, Thomas Budde, Thomas Munsch

Engineering Genetically Encoded Nanosensors for Real-Time In Vivo Measurements of Citrate Concentrations
Jennifer C. Ewald, Sabrina Reich, Stephan Baumann, Wolf B. Frommer, Nicola Zamboni

Cup Blocks the Precocious Activation of the Orb Autoregulatory Loop
Li Chin Wong, Paul Schedl

The Global Transcriptional Response of Fission Yeast to Hydrogen Sulfide
Xu Jia, Weizhi He, Alastair I. H. Murchie, Dongrong Chen

Syndecan-4 Is Essential for Development of Concentric Myocardial Hypertrophy via Stretch-Induced Activation of the Calcineurin-NFAT Pathway
Alexandra V. Finsen, Ida G. Lunde, Ivar Sjaastad, Even K. Østli, Marianne Lyngra, Hilde O. Jarstadmarken, Almira Hasic, Ståle Nygård, Sarah A. Wilcox-Adelman, Paul F. Goetinck, Torstein Lyberg, Biljana Skrbic, Geir Florholmen, Theis Tønnessen, William E. Louch, Srdjan Djurovic, Cathrine R. Carlson, Geir Christensen

Membrane-Type-3 Matrix Metalloproteinase (MT3-MMP) Functions as a Matrix Composition-Dependent Effector of Melanoma Cell Invasion
Olga Tatti, Mariliina Arjama, Annamari Ranki, Stephen J. Weiss, Jorma Keski-Oja, Kaisa Lehti

Characterization of Abcc4 Gene Amplification in Stepwise-Selected Mouse J774 Macrophages Resistant to the Topoisomerase II Inhibitor Ciprofloxacin
Béatrice Marquez, Geneviève Ameye, Coralie M. Vallet, Paul M. Tulkens, Hélène A. Poirel, Françoise Van Bambeke

AcrB Trimer Stability and Efflux Activity, Insight from Mutagenesis Studies
Linliang Yu, Wei Lu, Yinan Wei

Dopamine Transporter (DAT1) and Dopamine Receptor D4 (DRD4) Genotypes Differentially Impact on Electrophysiological Correlates of Error Processing
Stefanie C. Biehl, Thomas Dresler, Andreas Reif, Peter Scheuerpflug, Jürgen Deckert, Martin J. Herrmann

Nascentome Analysis Uncovers Futile Protein Synthesis in Escherichia coli
Koreaki Ito, Yuhei Chadani, Kenta Nakamori, Shinobu Chiba, Yoshinori Akiyama, Tatsuhiko Abo

A Tissue-Specific Approach to the Analysis of Metabolic Changes in Caenorhabditis elegans
Jürgen Hench, Ivana Bratić Hench, Claire Pujol, Sabine Ipsen, Susanne Brodesser, Arnaud Mourier, Markus Tolnay, Stephan Frank, Aleksandra Trifunović

Direct Sensing of Endothelial Oxidants by Vascular Endothelial Growth Factor Receptor-2 and c-Src
Monica Lee, Wing C. Choy, Md. Ruhul Abid

The Role of Dicer Protein Partners in the Processing of MicroRNA Precursors
Edyta Koscianska, Julia Starega-Roslan, Wlodzimierz J. Krzyzosiak

Persistent Expression of Hepatitis C Virus Non-Structural Proteins Leads to Increased Autophagy and Mitochondrial Injury in Human Hepatoma Cells
Victor C. Chu, Sayanti Bhattacharya, Ann Nomoto, Jiahui Lin, Syed Kashif Zaidi, Terry D. Oberley, Steven A. Weinman, Salman Azhar, Ting-Ting Huang

Performance of the QuickVue Influenza A+B Rapid Test for Pandemic H1N1 (2009) Virus Infection in Adults
Wolfgang Poeppl, Harald Herkner, Heinz Burgmann, Tom Pustelnik, Gerhard Mooseder, Theresia Popow-Kraupp, Monika Redlberger-Fritz

Structural Position Correlation Analysis (SPCA) for Protein Family
Qi-Shi Du, Jian-Zong Meng, Cheng-Hua Wang, Si-Yu Long, Ri-Bo Huang

C-Peptide Increases Na,K-ATPase Expression via PKC- and MAP Kinase-Dependent Activation of Transcription Factor ZEB in Human Renal Tubular Cells
Dana Galuska, Sergej Pirkmajer, Romain Barrès, Karin Ekberg, John Wahren, Alexander V. Chibalin

LKB1 Is an Essential Regulator of Spermatozoa Release during Spermiation in the Mammalian Testis
Fiona C. Denison, Lee B. Smith, Phillip J. Muckett, Laura O'Hara, David Carling, Angela Woods

How Molecular Competition Influences Fluxes in Gene Expression Networks
Dirk De Vos, Frank J. Bruggeman, Hans V. Westerhoff, Barbara M. Bakker

Solutions to the Cocktail Party Problem in Insects: Selective Filters, Spatial Release from Masking and Gain Control in Tropical Crickets
Arne K. D. Schmidt, Heiner Römer

Mining Relational Paths in Integrated Biomedical Data
Bing He, Jie Tang, Ying Ding, Huijun Wang, Yuyin Sun, Jae Hong Shin, Bin Chen, Ganesh Moorthy, Judy Qiu, Pankaj Desai, David J. Wild

Transcriptional Regulation of Ribosome Components Are Determined by Stress According to Cellular Compartments in Arabidopsis thaliana
Rodnay Sormani, Céline Masclaux-Daubresse, Françoise Daniele-Vedele, Fabien Chardon

A Fungal P450 (CYP5136A3) Capable of Oxidizing Polycyclic Aromatic Hydrocarbons and Endocrine Disrupting Alkylphenols: Role of Trp129 and Leu324
Khajamohiddin Syed, Aleksey Porollo, Ying Wai Lam, Jagjit S. Yadav

Stimulus-Dependent Adjustment of Reward Prediction Error in the Midbrain
Hiromasa Takemura, Kazuyuki Samejima, Rufin Vogels, Masamichi Sakagami, Jiro Okuda

Accessible Surfaces of Beta Proteins Increase with Increasing Protein Molecular Mass More Rapidly than Those of Other Proteins
Anna V. Glyakina, Natalya S. Bogatyreva, Oxana V. Galzitskaya

The Tyrosine Kinase Inhibitor Dasatinib Induces a Marked Adipogenic Differentiation of Human Multipotent Mesenchymal Stromal Cells
Adriana Borriello, Ilaria Caldarelli, Maria Assunta Basile, Debora Bencivenga, Annunziata Tramontano, Silverio Perrotta, Fulvio Della Ragione, Adriana Oliva

Substrate Adhesion Regulates Sealing Zone Architecture and Dynamics in Cultured Osteoclasts
Fabian Anderegg, Dafna Geblinger, Peter Horvath, Mirren Charnley, Marcus Textor, Lia Addadi, Benjamin Geiger

Biochemical and Molecular Mechanisms of Folate Transport in Rat Pancreas; Interference with Ethanol Ingestion
Nissar Ahmad Wani, Ritambhara Nada, Jyotdeep Kaur

Modulation of Thyroid Hormone-Dependent Gene Expression in Xenopus laevis by INhibitor of Growth (ING) Proteins
Caren C. Helbing, Mary J. Wagner, Katherine Pettem, Jill Johnston, Rachel A. Heimeier, Nik Veldhoen, Frank R. Jirik, Yun-Bo Shi, Leon W. Browder

Localization of ASV Integrase-DNA Contacts by Site-Directed Crosslinking and their Structural Analysis
Elena Peletskaya, Mark Andrake, Alla Gustchina, George Merkel, Jerry Alexandratos, Dongwen Zhou, Ravi S. Bojja, Tadashi Satoh, Mikhail Potapov, Alex Kogon, Viktor Potapov, Alexander Wlodawer, Anna Marie Skalka

SAF-A Forms a Complex with BRG1 and Both Components Are Required for RNA Polymerase II Mediated Transcription
Dzeneta Vizlin-Hodzic, Rikard Runnberg, Jessica Ryme, Stina Simonsson, Tomas Simonsson

ZipA Binds to FtsZ with High Affinity and Enhances the Stability of FtsZ Protofilaments
Anuradha Kuchibhatla, Anusri Bhattacharya, Dulal Panda

PTEN Modulates miR-21 Processing via RNA-Regulatory Protein RNH1
Youn-Jae Kim, Se-Jeong Park, Eun Young Choi, Sol Kim, Hee Jin Kwak, Byong Chul Yoo, Heon Yoo, Seung-Hoon Lee, Daesoo Kim, Jong Bae Park, Jong Heon Kim

Rev-Free HIV-1 Gene Delivery System for Targeting Rev-RRE-Crm1 Nucleocytoplasmic RNA Transport Pathway
Narasimhachar Srinivasakumar

Alkyl-Glycerol Rescues Plasmalogen Levels and Pathology of Ether-Phospholipid Deficient Mice
Pedro Brites, Ana Sofia Ferreira, Tiago Ferreira da Silva, Vera F. Sousa, Ana R. Malheiro, Marinus Duran, Hans R. Waterham, Myriam Baes, Ronald J. A. Wanders

TRESK Background K+ Channel Is Inhibited by PAR-1/MARK Microtubule Affinity-Regulating Kinases in Xenopus Oocytes
Gabriella Braun, Balázs Nemcsics, Péter Enyedi, Gábor Czirják

ProSAAS-Derived Peptides are Colocalized with Neuropeptide Y and Function as Neuropeptides in the Regulation of Food Intake
Jonathan H. Wardman, Iryna Berezniuk, Shi Di, Jeffrey G. Tasker, Lloyd D. Fricker

Scavenger Receptor Mediates Systemic RNA Interference in Ticks
Kyaw Min Aung, Damdinsuren Boldbaatar, Rika Umemiya-Shirafuji, Min Liao, Xuan Xuenan, Hiroshi Suzuki, Remil Linggatong Galay, Tetsuya Tanaka, Kozo Fujisaki

Structural Studies of β-Carbonic Anhydrase from the Green Alga Coccomyxa: Inhibitor Complexes with Anions and Acetazolamide
Shenghua Huang, Tobias Hainzl, Christin Grundström, Cecilia Forsman, Göran Samuelsson, A. Elisabeth Sauer-Eriksson

Yeast Based Small Molecule Screen for Inhibitors of SARS-CoV
Matthew Frieman, Dipanwita Basu, Krystal Matthews, Justin Taylor, Grant Jones, Raymond Pickles, Ralph Baric, Daniel A. Engel

Both hMutSα and hMutSß DNA Mismatch Repair Complexes Participate in 5-Fluorouracil Cytotoxicity
Akihiro Tajima, Moriya Iwaizumi, Stephanie Tseng-Rogenski, Betty L. Cabrera, John M. Carethers

Brachyury and Related Tbx Proteins Interact with the Mixl1 Homeodomain Protein and Negatively Regulate Mixl1 Transcriptional Activity
Lloyd A. Pereira, Michael S. Wong, Sue Mei Lim, Alexandra Sides, Edouard G. Stanley, Andrew G. Elefanty

Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement
Giuseppe Esposito, Caterina Scuderi, Marta Valenza, Giuseppina Ines Togna, Valentina Latina, Daniele De Filippis, Mariateresa Cipriano, Maria Rosaria Carratù, Teresa Iuvone, Luca Steardo

Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis
Daniele De Filippis, Giuseppe Esposito, Carla Cirillo, Mariateresa Cipriano, Benedicte Y. De Winter, Caterina Scuderi, Giovanni Sarnelli, Rosario Cuomo, Luca Steardo, Joris G. De Man, Teresa Iuvone

Glycosylation of Erythrocyte Spectrin and Its Modification in Visceral Leishmaniasis
Sajal Samanta, Devawati Dutta, Angana Ghoshal, Sumi Mukhopadhyay, Bibhuti Saha, Shyam Sundar, Saulius Jarmalavicius, Michael Forgber, Chhabinath Mandal, Peter Walden, Chitra Mandal

Bioinformatic Analysis and Post-Translational Modification Crosstalk Prediction of Lysine Acetylation
Zhike Lu, Zhongyi Cheng, Yingming Zhao, Samuel L. Volchenboum

Aquaporin-5: A Marker Protein for Proliferation and Migration of Human Breast Cancer Cells
Hyun Jun Jung, Ji-Young Park, Hyo-Sung Jeon, Tae-Hwan Kwon

Structure of the Bro1 Domain Protein BROX and Functional Analyses of the ALIX Bro1 Domain in HIV-1 Budding
Qianting Zhai, Michael B. Landesman, Howard Robinson, Wesley I. Sundquist, Christopher P. Hill

DNA Electrophoretic Migration Patterns Change after Exposure of Jurkat Cells to a Single Intense Nanosecond Electric Pulse
Stefania Romeo, Luigi Zeni, Maurizio Sarti, Anna Sannino, Maria Rosaria Scarfì, P. Thomas Vernier, Olga Zeni

DNA Damage in Plant Herbarium Tissue
Martijn Staats, Argelia Cuenca, James E. Richardson, Ria Vrielink-van Ginkel, Gitte Petersen, Ole Seberg, Freek T. Bakker

The Metabolic Reprogramming Evoked by Nitrosative Stress Triggers the Anaerobic Utilization of Citrate in Pseudomonas fluorescens
Christopher Auger, Joseph Lemire, Dominic Cecchini, Adam Bignucolo, Vasu D. Appanna

Recruitment of Oct4 Protein to UV-Damaged Chromatin in Embryonic Stem Cells
Eva Bártová, Gabriela Šustáčková, Lenka Stixová, Stanislav Kozubek, Soňa Legartová, Veronika Foltánková

Conserved and Divergent Roles of Bcr1 and CFEM Proteins in Candida parapsilosis and Candida albicans
Chen Ding, Genevieve M. Vidanes, Sarah L. Maguire, Alessandro Guida, John M. Synnott, David R. Andes, Geraldine Butler

SUMO-SIM Interactions Regulate the Activity of RGSZ2 Proteins
Javier Garzón, María Rodríguez-Muñoz, Ana Vicente-Sánchez, María Ángeles García-López, Ricardo Martínez-Murillo, Thierry Fischer, Pilar Sánchez-Blázquez

Corneal Alterations during Combined Therapy with Cyclodextrin/Allopregnanolone and Miglustat in a Knock-Out Mouse Model of NPC1 Disease
Marine Hovakimyan, Jana Petersen, Fabian Maass, Maria Reichard, Martin Witt, Jan Lukas, Oliver Stachs, Rudolf Guthoff, Arndt Rolfs, Andreas Wree

Algae as Protein Factories: Expression of a Human Antibody and the Respective Antigen in the Diatom Phaeodactylum tricornutum
Franziska Hempel, Julia Lau, Andreas Klingl, Uwe G. Maier

Actin-Independent Behavior and Membrane Deformation Exhibited by the Four-Transmembrane Protein M6a
Yasufumi Sato, Naoki Watanabe, Nanae Fukushima, Sakura Mita, Tatsumi Hirata

Cytochrome P450 1 Genes in Birds: Evolutionary Relationships and Transcription Profiles in Chicken and Japanese Quail Embryos
Maria E. Jönsson, Bruce R. Woodin, John J. Stegeman, Björn Brunström

Structural Constraints on the Covariance Matrix Derived from Multiple Aligned Protein Sequences
William R. Taylor, Michael I. Sadowski

SLO-2 Is Cytoprotective and Contributes to Mitochondrial Potassium Transport
Andrew P. Wojtovich, Teresa A. Sherman, Sergiy M. Nadtochiy, William R. Urciuoli, Paul S. Brookes, Keith Nehrke

Mannose Receptor (MR) Engagement by Mesothelin GPI Anchor Polarizes Tumor-Associated Macrophages and Is Blocked by Anti-MR Human Recombinant Antibody
Denarda Dangaj, Karen L. Abbott, Ananda Mookerjee, Aizhi Zhao, Pamela S. Kirby, Raphael Sandaltzopoulos, Daniel J. Powell, Antonin Lamazière, Don L. Siegel, Claude Wolf, Nathalie Scholler

Balance between MKK6 and MKK3 Mediates p38 MAPK Associated Resistance to Cisplatin in NSCLC
Eva M. Galan-Moya, Miguel A. de la Cruz-Morcillo, Maria Llanos Valero, Juan L. Callejas-Valera, Pedro Melgar-Rojas, Javier Hernadez Losa, Mayte Salcedo, Antonio Fernández-Aramburo, Santiago Ramon y. Cajal, Ricardo Sánchez-Prieto

Lipoglycans Contribute to Innate Immune Detection of Mycobacteria
Shyam Krishna, Aurélie Ray, Shiv K. Dubey, Gérald Larrouy-Maumus, Christian Chalut, Romain Castanier, Audrey Noguera, Martine Gilleron, Germain Puzo, Alain Vercellone, K. Madhavan Nampoothiri, Jérôme Nigou

UNC93B1 Physically Associates with Human TLR8 and Regulates TLR8-Mediated Signaling
Hiroki Itoh, Megumi Tatematsu, Ayako Watanabe, Katsunori Iwano, Kenji Funami, Tsukasa Seya, Misako Matsumoto

Selective Ion Changes during Spontaneous Mitochondrial Transients in Intact Astrocytes
Guillaume Azarias, Jean-Yves Chatton

Small Interfering RNA against Transcription Factor STAT6 Leads to Increased Cholesterol Synthesis in Lung Cancer Cell Lines
Richa Dubey, Ravindresh Chhabra, Neeru Saini

Generation of Variants in Listeria monocytogenes Continuous-Flow Biofilms Is Dependent on Radical-Induced DNA Damage and RecA-Mediated Repair
Stijn van der Veen, Tjakko Abee

Identification of Lactoferricin B Intracellular Targets Using an Escherichia coli Proteome Chip
Yu-Hsuan Tu, Yu-Hsuan Ho, Ying-Chih Chuang, Po-Chung Chen, Chien-Sheng Chen

Concentration Dependent Ion Selectivity in VDAC: A Molecular Dynamics Simulation Study
Eva-Maria Krammer, Fabrice Homblé, Martine Prévost

Chemical Defense of the Eastern Newt (Notophthalmus viridescens): Variation in Efficiency against Different Consumers and in Different Habitats
Zachary H. Marion, Mark E. Hay

Improving the Alignment Quality of Consistency Based Aligners with an Evaluation Function Using Synonymous Protein Words
Hsin-Nan Lin, Cédric Notredame, Jia-Ming Chang, Ting-Yi Sung, Wen-Lian Hsu

Human Alveolar Epithelial Cell Injury Induced by Cigarette Smoke
Beata Kosmider, Elise M. Messier, Hong Wei Chu, Robert J. Mason

Redistribution of DAT/α-Synuclein Complexes Visualized by "In Situ" Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease
Arianna Bellucci, Laura Navarria, Elisa Falarti, Michela Zaltieri, Federica Bono, Ginetta Collo, Maria Grazia, Cristina Missale, PierFranco Spano

Impact of Host Cell Line Adaptation on Quasispecies Composition and Glycosylation of Influenza A Virus Hemagglutinin
Jana Verena Roedig, Erdmann Rapp, Dirk Höper, Yvonne Genzel, Udo Reichl

Suppression of Phospholipase Dγs Confers Increased Aluminum Resistance in Arabidopsis thaliana
Jian Zhao, Cunxi Wang, Mohamed Bedair, Ruth Welti, Lloyd W. Sumner, Ivan Baxter, Xuemin Wang

Genomic DNA Methylation Changes in Response to Folic Acid Supplementation in a Population-Based Intervention Study among Women of Reproductive Age
Krista S. Crider, Eoin P. Quinlivan, Robert J. Berry, Ling Hao, Zhu Li, David Maneval, Thomas P. Yang, Sonja A. Rasmussen, Quanhe Yang, Jiang-Hui Zhu, Dale J. Hu, Lynn B. Bailey

Role of NADPH Oxidase versus Neutrophil Proteases in Antimicrobial Host Defense
R. Robert Vethanayagam, Nikolaos G. Almyroudis, Melissa J. Grimm, David C. Lewandowski, Christine T. N. Pham, Timothy S. Blackwell, Ruta Petraitiene, Vidmantas Petraitis, Thomas J. Walsh, Constantin F. Urban, Brahm H. Segal

Disruption of Spectrin-Like Cytoskeleton in Differentiating Keratinocytes by PKCδ Activation Is Associated with Phosphorylated Adducin
Kong-Nan Zhao, Paul P. Masci, Martin F. Lavin

DC-SIGN Increases the Affinity of HIV-1 Envelope Glycoprotein Interaction with CD4
Karolin Hijazi, Yufei Wang, Carlo Scala, Simon Jeffs, Colin Longstaff, Daniel Stieh, Beth Haggarty, Guido Vanham, Dominique Schols, Jan Balzarini, Ian M. Jones, James Hoxie, Robin Shattock, Charles G. Kelly

Estrogenic Plant Extracts Reverse Weight Gain and Fat Accumulation without Causing Mammary Gland or Uterine Proliferation
Elise F. Saunier, Omar I. Vivar, Andrea Rubenstein, Xiaoyue Zhao, Moshe Olshansky, Scott Baggett, Richard E. Staub, Mary Tagliaferri, Isaac Cohen, Terence P. Speed, John D. Baxter, Dale C. Leitman

Functional and Transcriptional Induction of Aquaporin-1 Gene by Hypoxia; Analysis of Promoter and Role of Hif-1α
Irene Abreu-Rodríguez, Rocío Sánchez Silva, Ana Paula Martins, Graça Soveral, Juan José Toledo-Aral, José López-Barneo, Miriam Echevarría

Omega-3 Fatty Acid Deficiency during Brain Maturation Reduces Neuronal and Behavioral Plasticity in Adulthood
Harsharan Singh Bhatia, Rahul Agrawal, Sandeep Sharma, Yi-Xin Huo, Zhe Ying, Fernando Gomez-Pinilla

Sequence Features of E. coli mRNAs Affect Their Degradation
Gal Lenz, Adi Doron-Faigenboim, Eliora Z. Ron, Tamir Tuller, Uri Gophna

Phosphorylation of AIB1 at Mitosis Is Regulated by CDK1/CYCLIN B
Macarena Ferrero, Juan Ferragud, Leonardo Orlando, Luz Valero, Manuel Sánchez del Pino, Rosa Farràs, Jaime Font de Mora

Transient Increase in Zn2+ in Hippocampal CA1 Pyramidal Neurons Causes Reversible Memory Deficit
Atsushi Takeda, Shunsuke Takada, Masatoshi Nakamura, Miki Suzuki, Haruna Tamano, Masaki Ando, Naoto Oku

Srv Mediated Dispersal of Streptococcal Biofilms Through SpeB Is Observed in CovRS+ Strains
Kristie L. Connolly, Amy K. Braden, Robert C. Holder, Sean D. Reid

Molecular Evolution of the Infrared Sensory Gene TRPA1 in Snakes and Implications for Functional Studies
Jie Geng, Dan Liang, Ke Jiang, Peng Zhang

Quantitative Mass Spectrometry Analysis Using PAcIFIC for the Identification of Plasma Diagnostic Biomarkers for Abdominal Aortic Aneurysm
Adelina E. Acosta-Martin, Alexandre Panchaud, Maggy Chwastyniak, Annabelle Dupont, Francis Juthier, Corinne Gautier, Brigitte Jude, Philippe Amouyel, David R. Goodlett, Florence Pinet

Protein 3D Structure Computed from Evolutionary Sequence Variation
Debora S. Marks, Lucy J. Colwell, Robert Sheridan, Thomas A. Hopf, Andrea Pagnani, Riccardo Zecchina, Chris Sander

Impact of the Lectin Chaperone Calnexin on the Stress Response, Virulence and Proteolytic Secretome of the Fungal Pathogen Aspergillus fumigatus
Margaret V. Powers-Fletcher, Kalyani Jambunathan, Jordan L. Brewer, Karthik Krishnan, Xizhi Feng, Amit K. Galande, David S. Askew

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Biophysics

AcrB Trimer Stability and Efflux Activity, Insight from Mutagenesis Studies
Linliang Yu, Wei Lu, Yinan Wei

Structural Position Correlation Analysis (SPCA) for Protein Family
Qi-Shi Du, Jian-Zong Meng, Cheng-Hua Wang, Si-Yu Long, Ri-Bo Huang

Chemotaxis in Densely Populated Tissue Determines Germinal Center Anatomy and Cell Motility: A New Paradigm for the Development of Complex Tissues
Jared B. Hawkins, Mark T. Jones, Paul E. Plassmann, David A. Thorley-Lawson

Localization of ASV Integrase-DNA Contacts by Site-Directed Crosslinking and their Structural Analysis
Elena Peletskaya, Mark Andrake, Alla Gustchina, George Merkel, Jerry Alexandratos, Dongwen Zhou, Ravi S. Bojja, Tadashi Satoh, Mikhail Potapov, Alex Kogon, Viktor Potapov, Alexander Wlodawer, Anna Marie Skalka

ZipA Binds to FtsZ with High Affinity and Enhances the Stability of FtsZ Protofilaments
Anuradha Kuchibhatla, Anusri Bhattacharya, Dulal Panda

Investigations on the Usefulness of CEACAMs as Potential Imaging Targets for Molecular Imaging Purposes
Markus Heine, Peter Nollau, Christoph Masslo, Peter Nielsen, Barbara Freund, Oliver T. Bruns, Rudolph Reimer, Heinrich Hohenberg, Kersten Peldschus, Harald Ittrich, Udo Schumacher

Scavenger Receptor Mediates Systemic RNA Interference in Ticks
Kyaw Min Aung, Damdinsuren Boldbaatar, Rika Umemiya-Shirafuji, Min Liao, Xuan Xuenan, Hiroshi Suzuki, Remil Linggatong Galay, Tetsuya Tanaka, Kozo Fujisaki

Structural Studies of β-Carbonic Anhydrase from the Green Alga Coccomyxa: Inhibitor Complexes with Anions and Acetazolamide
Shenghua Huang, Tobias Hainzl, Christin Grundström, Cecilia Forsman, Göran Samuelsson, A. Elisabeth Sauer-Eriksson

MAP4 Mechanism that Stabilizes Mitochondrial Permeability Transition in Hypoxia: Microtubule Enhancement and DYNLT1 Interaction with VDAC1
Ya-dong Fang, Xue Xu, Yong-ming Dang, Yi-ming Zhang, Jia-ping Zhang, Jiong-yu Hu, Qiong Zhang, Xia Dai, Miao Teng, Dong-xia Zhang, Yue-sheng Huang

Structure of the Bro1 Domain Protein BROX and Functional Analyses of the ALIX Bro1 Domain in HIV-1 Budding
Qianting Zhai, Michael B. Landesman, Howard Robinson, Wesley I. Sundquist, Christopher P. Hill

DNA Electrophoretic Migration Patterns Change after Exposure of Jurkat Cells to a Single Intense Nanosecond Electric Pulse
Stefania Romeo, Luigi Zeni, Maurizio Sarti, Anna Sannino, Maria Rosaria Scarfì, P. Thomas Vernier, Olga Zeni

SUMO-SIM Interactions Regulate the Activity of RGSZ2 Proteins
Javier Garzón, María Rodríguez-Muñoz, Ana Vicente-Sánchez, María Ángeles García-López, Ricardo Martínez-Murillo, Thierry Fischer, Pilar Sánchez-Blázquez

Structural Constraints on the Covariance Matrix Derived from Multiple Aligned Protein Sequences
William R. Taylor, Michael I. Sadowski

Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells
Sun-Young Yoon, Kyu-Tae Kim, Seong Jin Jo, A-Ri Cho, Soon-Ik Jeon, Hyung-Do Choi, Kyu Han Kim, Gun-Sik Park, Jeong-Ki Pack, Oh Sang Kwon, Woong-Yang Park

Concentration Dependent Ion Selectivity in VDAC: A Molecular Dynamics Simulation Study
Eva-Maria Krammer, Fabrice Homblé, Martine Prévost

Improving the Alignment Quality of Consistency Based Aligners with an Evaluation Function Using Synonymous Protein Words
Hsin-Nan Lin, Cédric Notredame, Jia-Ming Chang, Ting-Yi Sung, Wen-Lian Hsu

Behavioral Mechanism during Human Sperm Chemotaxis: Involvement of Hyperactivation
Leah Armon, Michael Eisenbach

Functional and Transcriptional Induction of Aquaporin-1 Gene by Hypoxia; Analysis of Promoter and Role of Hif-1α
Irene Abreu-Rodríguez, Rocío Sánchez Silva, Ana Paula Martins, Graça Soveral, Juan José Toledo-Aral, José López-Barneo, Miriam Echevarría

Antibody Labelling of Resilin in Energy Stores for Jumping in Plant Sucking Insects
Malcolm Burrows, Jolanta A. Borycz, Stephen R. Shaw, Christopher M. Elvin, Ian A. Meinertzhagen

Sequence Features of E. coli mRNAs Affect Their Degradation
Gal Lenz, Adi Doron-Faigenboim, Eliora Z. Ron, Tamir Tuller, Uri Gophna

MRI Findings for Frozen Shoulder Evaluation: Is the Thickness of the Coracohumeral Ligament a Valuable Diagnostic Tool?
Jin-qing Li, Kang-lai Tang, Jian Wang, Qi-yu Li, Hao-tong Xu, Hui-feng Yang, Li-wen Tan, Kai-jun Liu, Shao-xiang Zhang

Protein 3D Structure Computed from Evolutionary Sequence Variation
Debora S. Marks, Lucy J. Colwell, Robert Sheridan, Thomas A. Hopf, Andrea Pagnani, Riccardo Zecchina, Chris Sander

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Biotechnology

Cost Effectiveness of Fibrosis Assessment Prior to Treatment for Chronic Hepatitis C Patients
Shan Liu, Michaël Schwarzinger, Fabrice Carrat, Jeremy D. Goldhaber-Fiebert

Engineering Genetically Encoded Nanosensors for Real-Time In Vivo Measurements of Citrate Concentrations
Jennifer C. Ewald, Sabrina Reich, Stephan Baumann, Wolf B. Frommer, Nicola Zamboni

Post-Transcriptional Silencing of Flavonol Synthase mRNA in Tobacco Leads to Fruits with Arrested Seed Set
Monika Mahajan, Paramvir Singh Ahuja, Sudesh Kumar Yadav

In Vitro Model of Vascularized Bone: Synergizing Vascular Development and Osteogenesis
Cristina Correia, Warren L. Grayson, Miri Park, Daphne Hutton, Bin Zhou, X. Edward Guo, Laura Niklason, Rui A. Sousa, Rui L. Reis, Gordana Vunjak-Novakovic

Characterization of Abcc4 Gene Amplification in Stepwise-Selected Mouse J774 Macrophages Resistant to the Topoisomerase II Inhibitor Ciprofloxacin
Béatrice Marquez, Geneviève Ameye, Coralie M. Vallet, Paul M. Tulkens, Hélène A. Poirel, Françoise Van Bambeke

Long-Distance Translocation of Protein during Morphogenesis of the Fruiting Body in the Filamentous Fungus, Agaricus bisporus
Benjamin M. Woolston, Carl Schlagnhaufer, Jack Wilkinson, Jeffrey Larsen, Zhixin Shi, Kimberly M. Mayer, Donald S. Walters, Wayne R. Curtis, C. Peter Romaine

Identification of the Midgut Microbiota of An. stephensi and An. maculipennis for Their Application as a Paratransgenic Tool against Malaria
Navid Dinparast Djadid, Hoda Jazayeri, Abbasali Raz, Guido Favia, Ignacio Ricci, Sedigheh Zakeri

A Real-Time PCR Antibiogram for Drug-Resistant Sepsis
John R. Waldeisen, Tim Wang, Debkishore Mitra, Luke P. Lee

A Fungal P450 (CYP5136A3) Capable of Oxidizing Polycyclic Aromatic Hydrocarbons and Endocrine Disrupting Alkylphenols: Role of Trp129 and Leu324
Khajamohiddin Syed, Aleksey Porollo, Ying Wai Lam, Jagjit S. Yadav

The Tyrosine Kinase Inhibitor Dasatinib Induces a Marked Adipogenic Differentiation of Human Multipotent Mesenchymal Stromal Cells
Adriana Borriello, Ilaria Caldarelli, Maria Assunta Basile, Debora Bencivenga, Annunziata Tramontano, Silverio Perrotta, Fulvio Della Ragione, Adriana Oliva

Substrate Adhesion Regulates Sealing Zone Architecture and Dynamics in Cultured Osteoclasts
Fabian Anderegg, Dafna Geblinger, Peter Horvath, Mirren Charnley, Marcus Textor, Lia Addadi, Benjamin Geiger

Neuroglobin-Deficiency Exacerbates Hif1A and c-FOS Response, but Does Not Affect Neuronal Survival during Severe Hypoxia In Vivo
Christian Ansgar Hundahl, Hendrik Luuk, Sten Ilmjärv, Birgitte Falktoft, Zindy Raida, Jonas Vikesaa, Lennart Friis-Hansen, Anders Hay-Schmidt

Potent Neutralization of Influenza A Virus by a Single-Domain Antibody Blocking M2 Ion Channel Protein
Guowei Wei, Weixu Meng, Haijiang Guo, Weiqi Pan, Jinsong Liu, Tao Peng, Ling Chen, Chang-You Chen

Phages Bearing Affinity Peptides to Bovine Rotavirus Differentiate the Virus from Other Viruses
Xin Wang, Guangxing Li, Yudong Ren, Xiaofeng Ren

Investigations on the Usefulness of CEACAMs as Potential Imaging Targets for Molecular Imaging Purposes
Markus Heine, Peter Nollau, Christoph Masslo, Peter Nielsen, Barbara Freund, Oliver T. Bruns, Rudolph Reimer, Heinrich Hohenberg, Kersten Peldschus, Harald Ittrich, Udo Schumacher

Yeast Based Small Molecule Screen for Inhibitors of SARS-CoV
Matthew Frieman, Dipanwita Basu, Krystal Matthews, Justin Taylor, Grant Jones, Raymond Pickles, Ralph Baric, Daniel A. Engel

Population Structure and Genetic Diversity in a Rice Core Collection (Oryza sativa L.) Investigated with SSR Markers
Peng Zhang, Jinquan Li, Xiaoling Li, Xiangdong Liu, Xingjuan Zhao, Yonggen Lu

Accurate Genome Relative Abundance Estimation Based on Shotgun Metagenomic Reads
Li C. Xia, Jacob A. Cram, Ting Chen, Jed A. Fuhrman, Fengzhu Sun

SNP/RD Typing of Mycobacterium tuberculosis Beijing Strains Reveals Local and Worldwide Disseminated Clonal Complexes
Anita C. Schürch, Kristin Kremer, Amber C. A. Hendriks, Benthe Freyee, Christopher R. E. McEvoy, Reinout van Crevel, Martin J. Boeree, Paul van Helden, Robin M. Warren, Roland J. Siezen, Dick van Soolingen

Generation of ESTs for Flowering Gene Discovery and SSR Marker Development in Upland Cotton
Deyong Lai, Huaizhu Li, Shuli Fan, Meizhen Song, Chaoyou Pang, Hengling Wei, Junjie Liu, Dong Wu, Wenfang Gong, Shuxun Yu

Can Arbuscular Mycorrhizal Fungi Reduce the Growth of Agricultural Weeds?
Rita S. L. Veiga, Jan Jansa, Emmanuel Frossard, Marcel G. A. van der Heijden

Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis
Daniele De Filippis, Giuseppe Esposito, Carla Cirillo, Mariateresa Cipriano, Benedicte Y. De Winter, Caterina Scuderi, Giovanni Sarnelli, Rosario Cuomo, Luca Steardo, Joris G. De Man, Teresa Iuvone

Generation of Glucose-Responsive Functional Islets with a Three-Dimensional Structure from Mouse Fetal Pancreatic Cells and iPS Cells In Vitro
Hiroki Saito, Masaki Takeuchi, Kazuhiro Chida, Atsushi Miyajima

DNA Electrophoretic Migration Patterns Change after Exposure of Jurkat Cells to a Single Intense Nanosecond Electric Pulse
Stefania Romeo, Luigi Zeni, Maurizio Sarti, Anna Sannino, Maria Rosaria Scarfì, P. Thomas Vernier, Olga Zeni

Algae as Protein Factories: Expression of a Human Antibody and the Respective Antigen in the Diatom Phaeodactylum tricornutum
Franziska Hempel, Julia Lau, Andreas Klingl, Uwe G. Maier

Identification of Lactoferricin B Intracellular Targets Using an Escherichia coli Proteome Chip
Yu-Hsuan Tu, Yu-Hsuan Ho, Ying-Chih Chuang, Po-Chung Chen, Chien-Sheng Chen

Redistribution of DAT/α-Synuclein Complexes Visualized by "In Situ" Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease
Arianna Bellucci, Laura Navarria, Elisa Falarti, Michela Zaltieri, Federica Bono, Ginetta Collo, Maria Grazia, Cristina Missale, PierFranco Spano

Impact of Host Cell Line Adaptation on Quasispecies Composition and Glycosylation of Influenza A Virus Hemagglutinin
Jana Verena Roedig, Erdmann Rapp, Dirk Höper, Yvonne Genzel, Udo Reichl

Suppression of Phospholipase Dγs Confers Increased Aluminum Resistance in Arabidopsis thaliana
Jian Zhao, Cunxi Wang, Mohamed Bedair, Ruth Welti, Lloyd W. Sumner, Ivan Baxter, Xuemin Wang

Estrogenic Plant Extracts Reverse Weight Gain and Fat Accumulation without Causing Mammary Gland or Uterine Proliferation
Elise F. Saunier, Omar I. Vivar, Andrea Rubenstein, Xiaoyue Zhao, Moshe Olshansky, Scott Baggett, Richard E. Staub, Mary Tagliaferri, Isaac Cohen, Terence P. Speed, John D. Baxter, Dale C. Leitman

Onset and Progression of Behavioral and Molecular Phenotypes in a Novel Congenic R6/2 Line Exhibiting Intergenerational CAG Repeat Stability
Randi-Michelle Cowin, Nghiem Bui, Deanna Graham, Jennie R. Green, Stephan Grueninger, Lisa A. Yuva-Paylor, Arsalan U. Syed, Andreas Weiss, Richard Paylor

Correlation Network Analysis Applied to Complex Biofilm Communities
Ana E. Duran-Pinedo, Bruce Paster, Ricardo Teles, Jorge Frias-Lopez

Dendrimer-Based Fluorescent Indicators: In Vitro and In Vivo Applications
Lorenzo Albertazzi, Marco Brondi, Giovanni M. Pavan, Sebastian Sulis Sato, Giovanni Signore, Barbara Storti, Gian Michele Ratto, Fabio Beltram

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Cell Biology

Modulation of Calcium-Dependent Inactivation of L-Type Ca2+ Channels via β-Adrenergic Signaling in Thalamocortical Relay Neurons
Vladan Rankovic, Peter Landgraf, Tatyana Kanyshkova, Petra Ehling, Sven G. Meuth, Michael R. Kreutz, Thomas Budde, Thomas Munsch

Down-Regulation of DNA Mismatch Repair Enhances Initiation and Growth of Neuroblastoma and Brain Tumour Multicellular Spheroids
Samuel L. Collins, Rodolphe Hervé, C. W. Keevil, Jeremy P. Blaydes, Jeremy S. Webb

Engineering Genetically Encoded Nanosensors for Real-Time In Vivo Measurements of Citrate Concentrations
Jennifer C. Ewald, Sabrina Reich, Stephan Baumann, Wolf B. Frommer, Nicola Zamboni

Syndecan-4 Is Essential for Development of Concentric Myocardial Hypertrophy via Stretch-Induced Activation of the Calcineurin-NFAT Pathway
Alexandra V. Finsen, Ida G. Lunde, Ivar Sjaastad, Even K. Østli, Marianne Lyngra, Hilde O. Jarstadmarken, Almira Hasic, Ståle Nygård, Sarah A. Wilcox-Adelman, Paul F. Goetinck, Torstein Lyberg, Biljana Skrbic, Geir Florholmen, Theis Tønnessen, William E. Louch, Srdjan Djurovic, Cathrine R. Carlson, Geir Christensen

Membrane-Type-3 Matrix Metalloproteinase (MT3-MMP) Functions as a Matrix Composition-Dependent Effector of Melanoma Cell Invasion
Olga Tatti, Mariliina Arjama, Annamari Ranki, Stephen J. Weiss, Jorma Keski-Oja, Kaisa Lehti

Nascentome Analysis Uncovers Futile Protein Synthesis in Escherichia coli
Koreaki Ito, Yuhei Chadani, Kenta Nakamori, Shinobu Chiba, Yoshinori Akiyama, Tatsuhiko Abo

Direct Sensing of Endothelial Oxidants by Vascular Endothelial Growth Factor Receptor-2 and c-Src
Monica Lee, Wing C. Choy, Md. Ruhul Abid

Persistent Expression of Hepatitis C Virus Non-Structural Proteins Leads to Increased Autophagy and Mitochondrial Injury in Human Hepatoma Cells
Victor C. Chu, Sayanti Bhattacharya, Ann Nomoto, Jiahui Lin, Syed Kashif Zaidi, Terry D. Oberley, Steven A. Weinman, Salman Azhar, Ting-Ting Huang

Integrin-α5 Coordinates Assembly of Posterior Cranial Placodes in Zebrafish and Enhances Fgf-Dependent Regulation of Otic/Epibranchial Cells
Neha Bhat, Bruce B. Riley

The Oogenic Germline Starvation Response in C. elegans
Hannah S. Seidel, Judith Kimble

Striking Denervation of Neuromuscular Junctions without Lumbar Motoneuron Loss in Geriatric Mouse Muscle
Ruth Jinfen Chai, Jana Vukovic, Sarah Dunlop, Miranda D. Grounds, Thea Shavlakadze

LKB1 Is an Essential Regulator of Spermatozoa Release during Spermiation in the Mammalian Testis
Fiona C. Denison, Lee B. Smith, Phillip J. Muckett, Laura O'Hara, David Carling, Angela Woods

A Novel Multiplex Cell Viability Assay for High-Throughput RNAi Screening
Daniel F. Gilbert, Gerrit Erdmann, Xian Zhang, Anja Fritzsche, Kubilay Demir, Andreas Jaedicke, Katja Muehlenberg, Erich E. Wanker, Michael Boutros

Transcriptional Regulation of Ribosome Components Are Determined by Stress According to Cellular Compartments in Arabidopsis thaliana
Rodnay Sormani, Céline Masclaux-Daubresse, Françoise Daniele-Vedele, Fabien Chardon

A Novel Human TPIP Splice-Variant (TPIP-C2) mRNA, Expressed in Human and Mouse Tissues, Strongly Inhibits Cell Growth in HeLa Cells
Rasmi Rekha Mishra, Jitendra Kumar Chaudhary, Gagan Deep Bajaj, Pramod C. Rath

Corneal Epithelium Expresses a Variant of P2X7 Receptor in Health and Disease
Courtney Mankus, Celeste Rich, Martin Minns, Vickery Trinkaus-Randall

The Tyrosine Kinase Inhibitor Dasatinib Induces a Marked Adipogenic Differentiation of Human Multipotent Mesenchymal Stromal Cells
Adriana Borriello, Ilaria Caldarelli, Maria Assunta Basile, Debora Bencivenga, Annunziata Tramontano, Silverio Perrotta, Fulvio Della Ragione, Adriana Oliva

Substrate Adhesion Regulates Sealing Zone Architecture and Dynamics in Cultured Osteoclasts
Fabian Anderegg, Dafna Geblinger, Peter Horvath, Mirren Charnley, Marcus Textor, Lia Addadi, Benjamin Geiger

Identification of a Novel Response Regulator, Crr1, That Is Required for Hydrogen Peroxide Resistance in Candida albicans
Catherine R. Bruce, Deborah A. Smith, David Rodgers, Alessandra da Silva Dantas, Donna M. MacCallum, Brian A. Morgan, Janet Quinn

Tyrosine Phosphorylation of Rac1: A Role in Regulation of Cell Spreading
Fumin Chang, Christopher Lemmon, Daniel Lietha, Michael Eck, Lewis Romer

SAF-A Forms a Complex with BRG1 and Both Components Are Required for RNA Polymerase II Mediated Transcription
Dzeneta Vizlin-Hodzic, Rikard Runnberg, Jessica Ryme, Stina Simonsson, Tomas Simonsson

Meiosis in Mice without a Synaptonemal Complex
Anna Kouznetsova, Ricardo Benavente, Albert Pastink, Christer Höög

Investigations on the Usefulness of CEACAMs as Potential Imaging Targets for Molecular Imaging Purposes
Markus Heine, Peter Nollau, Christoph Masslo, Peter Nielsen, Barbara Freund, Oliver T. Bruns, Rudolph Reimer, Heinrich Hohenberg, Kersten Peldschus, Harald Ittrich, Udo Schumacher

Runx1 Loss Minimally Impacts Long-Term Hematopoietic Stem Cells
Xiongwei Cai, Justin J. Gaudet, James K. Mangan, Michael J. Chen, Maria Elena De Obaldia, Zaw Oo, Patricia Ernst, Nancy A. Speck

Nox2 Oxidase Activity Accounts for the Oxidative Stress and Vasomotor Dysfunction in Mouse Cerebral Arteries following Ischemic Stroke
T. Michael De Silva, Vanessa H. Brait, Grant R. Drummond, Christopher G. Sobey, Alyson A. Miller

Brachyury and Related Tbx Proteins Interact with the Mixl1 Homeodomain Protein and Negatively Regulate Mixl1 Transcriptional Activity
Lloyd A. Pereira, Michael S. Wong, Sue Mei Lim, Alexandra Sides, Edouard G. Stanley, Andrew G. Elefanty

Differential Roles of HOW in Male and Female Drosophila Germline Differentiation
Adrian C. Monk, Nicole A. Siddall, Barbara Fraser, Eileen A. McLaughlin, Gary R. Hime

MAP4 Mechanism that Stabilizes Mitochondrial Permeability Transition in Hypoxia: Microtubule Enhancement and DYNLT1 Interaction with VDAC1
Ya-dong Fang, Xue Xu, Yong-ming Dang, Yi-ming Zhang, Jia-ping Zhang, Jiong-yu Hu, Qiong Zhang, Xia Dai, Miao Teng, Dong-xia Zhang, Yue-sheng Huang

Generation of Glucose-Responsive Functional Islets with a Three-Dimensional Structure from Mouse Fetal Pancreatic Cells and iPS Cells In Vitro
Hiroki Saito, Masaki Takeuchi, Kazuhiro Chida, Atsushi Miyajima

Constitutive MAP Kinase Activation in Hematopoietic Stem Cells Induces a Myeloproliferative Disorder
Eva Chung, Chia-Lin Hsu, Motonari Kondo

Mice Null for Calsequestrin 1 Exhibit Deficits in Functional Performance and Sarcoplasmic Reticulum Calcium Handling
Rotimi O. Olojo, Andrew P. Ziman, Erick O. Hernández-Ochoa, Paul D. Allen, Martin F. Schneider, Christopher W. Ward

DNA Electrophoretic Migration Patterns Change after Exposure of Jurkat Cells to a Single Intense Nanosecond Electric Pulse
Stefania Romeo, Luigi Zeni, Maurizio Sarti, Anna Sannino, Maria Rosaria Scarfì, P. Thomas Vernier, Olga Zeni

The Metabolic Reprogramming Evoked by Nitrosative Stress Triggers the Anaerobic Utilization of Citrate in Pseudomonas fluorescens
Christopher Auger, Joseph Lemire, Dominic Cecchini, Adam Bignucolo, Vasu D. Appanna

The GATA1-HS2 Enhancer Allows Persistent and Position-Independent Expression of a β-globin Transgene
Annarita Miccio, Valentina Poletti, Francesca Tiboni, Claudia Rossi, Antonella Antonelli, Fulvio Mavilio, Giuliana Ferrari

Concanavalin A/IFN-Gamma Triggers Autophagy-Related Necrotic Hepatocyte Death through IRGM1-Mediated Lysosomal Membrane Disruption
Chih-Peng Chang, Ming-Chen Yang, Huan-Yao Lei

High ACSL5 Transcript Levels Associate with Systemic Lupus Erythematosus and Apoptosis in Jurkat T Lymphocytes and Peripheral Blood Cells
Antonio Catalá-Rabasa, Dorothy Ndagire, Jose Mario Sabio, Maria Fedetz, Fuencisla Matesanz, Antonio Alcina

Actin-Independent Behavior and Membrane Deformation Exhibited by the Four-Transmembrane Protein M6a
Yasufumi Sato, Naoki Watanabe, Nanae Fukushima, Sakura Mita, Tatsumi Hirata

Aberrant Hedgehog Ligands Induce Progressive Pancreatic Fibrosis by Paracrine Activation of Myofibroblasts and Ductular Cells in Transgenic Zebrafish
In Hye Jung, Dawoon E. Jung, Young Nyun Park, Si Young Song, Seung Woo Park

Widespread Regulation of miRNA Biogenesis at the Dicer Step by the Cold-Inducible RNA-Binding Protein, RBM3
Julie Pilotte, Esther E. Dupont-Versteegden, Peter W. Vanderklish

UNC93B1 Physically Associates with Human TLR8 and Regulates TLR8-Mediated Signaling
Hiroki Itoh, Megumi Tatematsu, Ayako Watanabe, Katsunori Iwano, Kenji Funami, Tsukasa Seya, Misako Matsumoto

Small Interfering RNA against Transcription Factor STAT6 Leads to Increased Cholesterol Synthesis in Lung Cancer Cell Lines
Richa Dubey, Ravindresh Chhabra, Neeru Saini

Nicotinamide Inhibits Alkylating Agent-Induced Apoptotic Neurodegeneration in the Developing Rat Brain
Najeeb Ullah, Hae Young Lee, Muhammad Imran Naseer, Ikram Ullah, Joo Won Suh, Myeong Ok Kim

Crosstalk between JNK and SUMO Signaling Pathways: deSUMOylation Is Protective against H2O2-Induced Cell Injury
Marco Feligioni, Elisa Brambilla, Agata Camassa, Alessandra Sclip, Andrea Arnaboldi, Federica Morelli, Xanthi Antoniou, Tiziana Borsello

Human Alveolar Epithelial Cell Injury Induced by Cigarette Smoke
Beata Kosmider, Elise M. Messier, Hong Wei Chu, Robert J. Mason

CFTR Expression Analysis in Human Nasal Epithelial Cells by Flow Cytometry
Marit A. van Meegen, Suzanne W. J. Terheggen-Lagro, Cornelis K. van der Ent, Jeffrey M. Beekman

Disruption of Spectrin-Like Cytoskeleton in Differentiating Keratinocytes by PKCδ Activation Is Associated with Phosphorylated Adducin
Kong-Nan Zhao, Paul P. Masci, Martin F. Lavin

Gene Expression Profiling of Embryonic Human Neural Stem Cells and Dopaminergic Neurons from Adult Human Substantia Nigra
Hany E. S. Marei, Asma Althani, Nahla Afifi, Fabrizio Michetti, Mario Pescatori, Roberto Pallini, Patricia Casalbore, Carlo Cenciarelli, Philip Schwartz, Abd-Elmaksoud Ahmed

Phosphorylation of AIB1 at Mitosis Is Regulated by CDK1/CYCLIN B
Macarena Ferrero, Juan Ferragud, Leonardo Orlando, Luz Valero, Manuel Sánchez del Pino, Rosa Farràs, Jaime Font de Mora

Srv Mediated Dispersal of Streptococcal Biofilms Through SpeB Is Observed in CovRS+ Strains
Kristie L. Connolly, Amy K. Braden, Robert C. Holder, Sean D. Reid

Epithelial Cells Activate Plasmacytoid Dendritic Cells Improving Their Anti-HIV Activity
Christian Rodriguez Rodrigues, Mercedes Cabrini, Federico Remes Lenicov, Juan Sabatté, Ana Ceballos, Carolina Jancic, Silvina Raiden, Matías Ostrowski, Claudia Silberstein, Jorge Geffner

Impact of the Lectin Chaperone Calnexin on the Stress Response, Virulence and Proteolytic Secretome of the Fungal Pathogen Aspergillus fumigatus
Margaret V. Powers-Fletcher, Kalyani Jambunathan, Jordan L. Brewer, Karthik Krishnan, Xizhi Feng, Amit K. Galande, David S. Askew

Isolation of Radial Glia-Like Neural Stem Cells from Fetal and Adult Mouse Forebrain via Selective Adhesion to a Novel Adhesive Peptide-Conjugate
Károly Markó, Tímea Kőhidi, Nóra Hádinger, Márta Jelitai, Gábor Mező, Emília Madarász

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Chemistry

In Vitro Model of Vascularized Bone: Synergizing Vascular Development and Osteogenesis
Cristina Correia, Warren L. Grayson, Miri Park, Daphne Hutton, Bin Zhou, X. Edward Guo, Laura Niklason, Rui A. Sousa, Rui L. Reis, Gordana Vunjak-Novakovic

Discovery of Novel MDR-Mycobacterium tuberculosis Inhibitor by New FRIGATE Computational Screen
Christoph Scheich, Zoltán Szabadka, Beáta Vértessy, Vera Pütter, Vince Grolmusz, Markus Schade

Dietary Essential Amino Acids Affect the Reproduction of the Keystone Herbivore Daphnia pulex
Patrick Fink, Claudia Pflitsch, Kay Marin

Mining Relational Paths in Integrated Biomedical Data
Bing He, Jie Tang, Ying Ding, Huijun Wang, Yuyin Sun, Jae Hong Shin, Bin Chen, Ganesh Moorthy, Judy Qiu, Pankaj Desai, David J. Wild

Measurement of Warfarin in the Oral Fluid of Patients Undergoing Anticoagulant Oral Therapy
Silvia Ghimenti, Tommaso Lomonaco, Massimo Onor, Laura Murgia, Aldo Paolicchi, Roger Fuoco, Lucia Ruocco, Giovanni Pellegrini, Maria Giovanna Trivella, Fabio Di Francesco

Response of Soil Respiration to Soil Temperature and Moisture in a 50-Year-Old Oriental Arborvitae Plantation in China
Xinxiao Yu, Tianshan Zha, Zhuo Pang, Bin Wu, Xiaoping Wang, Guopeng Chen, Chunping Li, Jixin Cao, Guodong Jia, Xizhi Li, Hailong Wu

Localization of ASV Integrase-DNA Contacts by Site-Directed Crosslinking and their Structural Analysis
Elena Peletskaya, Mark Andrake, Alla Gustchina, George Merkel, Jerry Alexandratos, Dongwen Zhou, Ravi S. Bojja, Tadashi Satoh, Mikhail Potapov, Alex Kogon, Viktor Potapov, Alexander Wlodawer, Anna Marie Skalka

Chinese Herbal Medicines for the Treatment of Type A H1N1 Influenza: A Systematic Review of Randomized Controlled Trials
Wei Chen, Chi Eung Danforn Lim, Hong-Jun Kang, Jianping Liu

Glycosylation of Erythrocyte Spectrin and Its Modification in Visceral Leishmaniasis
Sajal Samanta, Devawati Dutta, Angana Ghoshal, Sumi Mukhopadhyay, Bibhuti Saha, Shyam Sundar, Saulius Jarmalavicius, Michael Forgber, Chhabinath Mandal, Peter Walden, Chitra Mandal

Structure of the Bro1 Domain Protein BROX and Functional Analyses of the ALIX Bro1 Domain in HIV-1 Budding
Qianting Zhai, Michael B. Landesman, Howard Robinson, Wesley I. Sundquist, Christopher P. Hill

Cytochrome P450 1 Genes in Birds: Evolutionary Relationships and Transcription Profiles in Chicken and Japanese Quail Embryos
Maria E. Jönsson, Bruce R. Woodin, John J. Stegeman, Björn Brunström

Chemical Defense of the Eastern Newt (Notophthalmus viridescens): Variation in Efficiency against Different Consumers and in Different Habitats
Zachary H. Marion, Mark E. Hay

Dendrimer-Based Fluorescent Indicators: In Vitro and In Vivo Applications
Lorenzo Albertazzi, Marco Brondi, Giovanni M. Pavan, Sebastian Sulis Sato, Giovanni Signore, Barbara Storti, Gian Michele Ratto, Fabio Beltram

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Computational Biology

An Open Source Simulation Model for Soil and Sediment Bioturbation
Katja Schiffers, Lorna Rachel Teal, Justin Mark John Travis, Martin Solan

Population Size Influences Amphibian Detection Probability: Implications for Biodiversity Monitoring Programs
Lorenzo G. Tanadini, Benedikt R. Schmidt

Improving Transmission Efficiency of Large Sequence Alignment/Map (SAM) Files
Muhammad Nazmus Sakib, Jijun Tang, W. Jim Zheng, Chin-Tser Huang

Correlation of Inter-Locus Polyglutamine Toxicity with CAG•CTG Triplet Repeat Expandability and Flanking Genomic DNA GC Content
Colm E. Nestor, Darren G. Monckton

Membrane-Type-3 Matrix Metalloproteinase (MT3-MMP) Functions as a Matrix Composition-Dependent Effector of Melanoma Cell Invasion
Olga Tatti, Mariliina Arjama, Annamari Ranki, Stephen J. Weiss, Jorma Keski-Oja, Kaisa Lehti

Dopamine Transporter (DAT1) and Dopamine Receptor D4 (DRD4) Genotypes Differentially Impact on Electrophysiological Correlates of Error Processing
Stefanie C. Biehl, Thomas Dresler, Andreas Reif, Peter Scheuerpflug, Jürgen Deckert, Martin J. Herrmann

Perspectives on the Use of Multiple Sclerosis Risk Genes for Prediction
Naghmeh Jafari, Linda Broer, Cornelia M. van Duijn, A. Cecile J. W. Janssens, Rogier Q. Hintzen

Structural Position Correlation Analysis (SPCA) for Protein Family
Qi-Shi Du, Jian-Zong Meng, Cheng-Hua Wang, Si-Yu Long, Ri-Bo Huang

Chromosome 3 Anomalies Investigated by Genome Wide SNP Analysis of Benign, Low Malignant Potential and Low Grade Ovarian Serous Tumours
Ashley H. Birch, Suzanna L. Arcand, Kathleen K. Oros, Kurosh Rahimi, A. Kevin Watters, Diane Provencher, Celia M. Greenwood, Anne-Marie Mes-Masson, Patricia N. Tonin

The Dichotomy in Degree Correlation of Biological Networks
Dapeng Hao, Chuanxing Li

How Molecular Competition Influences Fluxes in Gene Expression Networks
Dirk De Vos, Frank J. Bruggeman, Hans V. Westerhoff, Barbara M. Bakker

Statins Promote the Regression of Atherosclerosis via Activation of the CCR7-Dependent Emigration Pathway in Macrophages
Jonathan E. Feig, Yueting Shang, Noemi Rotllan, Yuliya Vengrenyuk, Chaowei Wu, Raanan Shamir, Ines Pineda Torra, Carlos Fernandez-Hernando, Edward A. Fisher, Michael J. Garabedian

The Gln32Lys Polymorphism in HSP22 of Zhikong Scallop Chlamys farreri Is Associated with Heat Tolerance
Chuanyan Yang, Lei Zhang, Lingling Wang, Huan Zhang, Limei Qiu, Vinu S. Siva, Linsheng Song

Unraveling the Design Principle for Motif Organization in Signaling Networks
Samrat Chatterjee, Dhiraj Kumar

Mining Relational Paths in Integrated Biomedical Data
Bing He, Jie Tang, Ying Ding, Huijun Wang, Yuyin Sun, Jae Hong Shin, Bin Chen, Ganesh Moorthy, Judy Qiu, Pankaj Desai, David J. Wild

Chemotaxis in Densely Populated Tissue Determines Germinal Center Anatomy and Cell Motility: A New Paradigm for the Development of Complex Tissues
Jared B. Hawkins, Mark T. Jones, Paul E. Plassmann, David A. Thorley-Lawson

Automatic Tumor-Stroma Separation in Fluorescence TMAs Enables the Quantitative High-Throughput Analysis of Multiple Cancer Biomarkers
Bernd Lahrmann, Niels Halama, Hans-Peter Sinn, Peter Schirmacher, Dirk Jaeger, Niels Grabe

A Fungal P450 (CYP5136A3) Capable of Oxidizing Polycyclic Aromatic Hydrocarbons and Endocrine Disrupting Alkylphenols: Role of Trp129 and Leu324
Khajamohiddin Syed, Aleksey Porollo, Ying Wai Lam, Jagjit S. Yadav

A Novel Human TPIP Splice-Variant (TPIP-C2) mRNA, Expressed in Human and Mouse Tissues, Strongly Inhibits Cell Growth in HeLa Cells
Rasmi Rekha Mishra, Jitendra Kumar Chaudhary, Gagan Deep Bajaj, Pramod C. Rath

Accessible Surfaces of Beta Proteins Increase with Increasing Protein Molecular Mass More Rapidly than Those of Other Proteins
Anna V. Glyakina, Natalya S. Bogatyreva, Oxana V. Galzitskaya

Evolution of Sexual Dimorphism in the Digit Ratio 2D:4D - Relationships with Body Size and Microhabitat Use in Iguanian Lizards
Camilla M. Gomes, Tiana Kohlsdorf

Corneal Epithelium Expresses a Variant of P2X7 Receptor in Health and Disease
Courtney Mankus, Celeste Rich, Martin Minns, Vickery Trinkaus-Randall

Localization of ASV Integrase-DNA Contacts by Site-Directed Crosslinking and their Structural Analysis
Elena Peletskaya, Mark Andrake, Alla Gustchina, George Merkel, Jerry Alexandratos, Dongwen Zhou, Ravi S. Bojja, Tadashi Satoh, Mikhail Potapov, Alex Kogon, Viktor Potapov, Alexander Wlodawer, Anna Marie Skalka

miRNA Expression Profiling of the Murine TH-MYCN Neuroblastoma Model Reveals Similarities with Human Tumors and Identifies Novel Candidate MiRNAs
Marta Terrile, Kenneth Bryan, Lynsey Vaughan, Albert Hallsworth, Hannah Webber, Louis Chesler, Raymond L. Stallings

Neuroglobin-Deficiency Exacerbates Hif1A and c-FOS Response, but Does Not Affect Neuronal Survival during Severe Hypoxia In Vivo
Christian Ansgar Hundahl, Hendrik Luuk, Sten Ilmjärv, Birgitte Falktoft, Zindy Raida, Jonas Vikesaa, Lennart Friis-Hansen, Anders Hay-Schmidt

ZipA Binds to FtsZ with High Affinity and Enhances the Stability of FtsZ Protofilaments
Anuradha Kuchibhatla, Anusri Bhattacharya, Dulal Panda

Employing Relative Entropy Techniques for Assessing Modifications in Animal Behavior
Minoru Kadota, Eric J. White, Shinsuke Torisawa, Kazuyoshi Komeyama, Tsutomu Takagi

Regulation of Virulence Gene Expression Resulting from Streptococcus pneumoniae and Nontypeable Haemophilus influenzae Interactions in Chronic Disease
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