Tuesday, May 10, 2011
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Lemons from Lemonade: Recycling Reactive Oxygen Species : We Beasties
Lemons from Lemonade: Recycling Reactive Oxygen Species : We Beasties
For a long time, researchers have known that macrophages use ROS to cope with bacterial invaders. There are enzymes like inducible nitric oxide synthase (iNOS) and NADPH oxidase that intentionally make ROS to deal with bacteria. But A West et al have now shown that macrophages can divert the waste stream from mitochondria, recycling these destructive molecules for their bacteriacidal activity.
For a long time, researchers have known that macrophages use ROS to cope with bacterial invaders. There are enzymes like inducible nitric oxide synthase (iNOS) and NADPH oxidase that intentionally make ROS to deal with bacteria. But A West et al have now shown that macrophages can divert the waste stream from mitochondria, recycling these destructive molecules for their bacteriacidal activity.
Natami Project Home Page
Natami Project Home Page
This hardware project is dedicated to the still innovative system architecture of the Commodore AMIGA computer.
The basic concept is straight: Get the original Amiga design up-to-date.
The NatAmi approach is to rebuild the original system
This means the system needs to be built from scratch. It will not use standard PC components when their adaption or implementation causes workarounds which limit preformance, functionality or usability. The priority is to build a very simple system design which is predictive, easy to use and fast responding like the amiga was/is.
The original creators put great effort and many thoughts into how to keep things simple. The NatAmi is intended to keep this guidline as the foundation of its system.
This concept is the project name: Native Amiga
The NatAmi does not revive or copy an A500/A4000. It will be a succeeding Amiga model not done by emulation - it is done by reconstruction. Up-to-date and good performing components are used to retain the efficiency. It will rely on the original philosophy - but remove old limitations.
The NatAmi is an AMIGA compatible machine, allowing you to natively run original Commodore Amiga software.
This hardware project is dedicated to the still innovative system architecture of the Commodore AMIGA computer.
The basic concept is straight: Get the original Amiga design up-to-date.
The NatAmi approach is to rebuild the original system
- without emulation
- without abstraction layers
- without legacy drawbacks
This means the system needs to be built from scratch. It will not use standard PC components when their adaption or implementation causes workarounds which limit preformance, functionality or usability. The priority is to build a very simple system design which is predictive, easy to use and fast responding like the amiga was/is.
The original creators put great effort and many thoughts into how to keep things simple. The NatAmi is intended to keep this guidline as the foundation of its system.
This concept is the project name: Native Amiga
The NatAmi does not revive or copy an A500/A4000. It will be a succeeding Amiga model not done by emulation - it is done by reconstruction. Up-to-date and good performing components are used to retain the efficiency. It will rely on the original philosophy - but remove old limitations.
The NatAmi is an AMIGA compatible machine, allowing you to natively run original Commodore Amiga software.
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