Friday, April 29, 2011
Thursday, April 28, 2011
System And Method For Holographic Optic Trap Bonding
System And Method For Holographic Optic Trap Bonding
This is what I was calling an optical crucible?
Does my work count as prior art?
What about the Replicator from Strar Trek?
This is what I was calling an optical crucible?
Does my work count as prior art?
What about the Replicator from Strar Trek?
Wednesday, April 27, 2011
Fwd: Crystallizing molecular assemblies that don’t exist (Metamodern)
---------- Forwarded message ----------
From: Newsfeed to Email Gateway <emlynoregan@gmail.com>
Date: Tue, Apr 26, 2011 at 5:01 PM
Subject: Crystallizing molecular assemblies that don't exist (Metamodern)
To: technologiclee@gmail.com
From: Newsfeed to Email Gateway <emlynoregan@gmail.com>
Date: Tue, Apr 26, 2011 at 5:01 PM
Subject: Crystallizing molecular assemblies that don't exist (Metamodern)
To: technologiclee@gmail.com
Crystallizing molecular assemblies that don't exist (04/26/11 18:20:15 UTC)
Leroy Cronin's group has pioneered the development of large, atomically precise metal oxide clusters (the polyoxometalates) with an eye to applications in nanotechnology. A recent publication shows why crystal engineering is a natural complement to this work — and to the engineering of self-assembling systems in general.
Here's an excerpt from the abstract (emphasis added):
Cations in control: crystal engineering polyoxometalate clusters using cation directed self-assembly
The synthetic engineering of anionic polyoxometalate (POM) clusters with predefined properties tailored to specific applications is a great challenge using routine "one-pot" POM syntheses. Under such conditions, difficulties often arise from the multitude of complex reaction pathways and self-assembly processes occurring in solution….the role of the cation facilitating the selective crystallization of a particular cluster type cannot be divorced from the reaction process since the crystallization process itself can help pull "virtual" building blocks into being….Consequently, this indicates that the process of crystallisation can have a profound effect on self-assembly at the molecular level. We therefore propose that the crystallization process itself may define the molecular structure of the cluster leading to the conundrum, which came first, the cluster or the crystal of the cluster?
There's a take-away message here for research groups working on self assembly (and likewise foldamers) based on a wide range of molecular systems:
The cooperativity of crystallization can select and stabilize structures that might be disfavored or unstable in solution, hence it may be easier to make crystalline arrays of self assembled structures than it is to make the structures themselves.
Rather than thinking in terms of two challenges in sequence — first, self assembly (or analogously, folding), then crystallization — it may be advantageous to reformulate these objectives as a single design problem leading to a one-step process that merges crystallization and assembly. Paradoxically, the combined challenge can be less than the sum of its parts — indeed, less than the challenge of the first step alone in the traditional methodology.
It goes without saying that a design-and-test cycle centered on crystalline products directly supports x-ray crystallography, the gold standard for determining structures with atomic resolution and geometric precision.
It's also well known that discrete units arrayed in porous crystals can be highly functional in themselves. The virtues of cross-linked enzyme crystals, for example, include stability and activity at elevated temperatures, in organic solvents, and under stringent industrial conditions.
--
http://www.google.com/profiles/technologiclee
Tuesday, April 26, 2011
Monday, April 25, 2011
Promethease - SNPedia
Promethease - SNPedia
Promethease is a tool to build a report based on SNPedia and a file of genotypes. Customers of testing services (23andMe, deCODEme, FamilyTreeDNA, Navigenics, ...) can use it to learn more about their DNA. It can also pool the data from multiple testing services. The program runs for approximately 3 hours. An optional $2 payment per run unlocks extra features and reduces runtime to approximately 5 minutes.
Promethease is a tool to build a report based on SNPedia and a file of genotypes. Customers of testing services (23andMe, deCODEme, FamilyTreeDNA, Navigenics, ...) can use it to learn more about their DNA. It can also pool the data from multiple testing services. The program runs for approximately 3 hours. An optional $2 payment per run unlocks extra features and reduces runtime to approximately 5 minutes.
Sunday, April 24, 2011
Saturday, April 23, 2011
CERN Press Release
CERN Press Release
Geneva, 22 April 2011. Around midnight this night CERN1’s Large Hadron Collider set a new world record for beam intensity at a hadron collider when it collided beams with a luminosity of 4.67 × 1032cm-2s-1. This exceeds the previous world record of 4.024 × 1032cm-2s-1, which was set by the US Fermi National Accelerator Laboratory’s Tevatron collider in 2010, and marks an important milestone in LHC commissioning.
Geneva, 22 April 2011. Around midnight this night CERN1’s Large Hadron Collider set a new world record for beam intensity at a hadron collider when it collided beams with a luminosity of 4.67 × 1032cm-2s-1. This exceeds the previous world record of 4.024 × 1032cm-2s-1, which was set by the US Fermi National Accelerator Laboratory’s Tevatron collider in 2010, and marks an important milestone in LHC commissioning.
Friday, April 22, 2011
Thursday, April 21, 2011
Wednesday, April 20, 2011
Saturday, April 16, 2011
Friday, April 15, 2011
Thursday, April 14, 2011
Wednesday, April 13, 2011
Tuesday, April 12, 2011
Monday, April 11, 2011
Saturday, April 9, 2011
Thursday, April 7, 2011
AnnMarie Thomas: Hands-on science with squishy circuits
AnnMarie Thomas: Hands-on science with squishy circuits | Video on TED.com
Published with Blogger-droid v1.6.7
Wednesday, April 6, 2011
Tuesday, April 5, 2011
Fwd: gel electrophoresis resolution
---------- Forwarded message ----------
From: Cory Tobin <cory.tobin@gmail.com>
Date: Tue, Apr 5, 2011 at 2:18 AM
Subject: Re: gel electrophoresis resolution
To: diybio@googlegroups.com
I've never actually seen a gel quite like this one. The tailing of
the bands is usually due to loading too much DNA in the well. But the
bands don't look that bright. Maybe there actually is a lot of DNA
there but since the background light isn't being filtered out it just
doesn't appear very bright?
Some general gel troubleshooting:
- Make sure the the loading buffer is the same as the running buffer.
For example, if you used 1X TAE in the gel and you are using a 5X
loading buffer, the loading buffer should be made with 5X TAE so when
it's diluted in your sample the pH and salt concentration is the same
as 1X TAE.
- Load less DNA
- Replace the running buffer, assuming you have been reusing it
multiple times. Not as critical if you're using TBE.
- Use a lower voltage.
- Fill the chamber lower. 5mm over the top of the gel is ideal.
Excessive buffer leads to smearing.
For more gel debugging and optimization check out a pdf called "The
Sourcebook" by the company Cambrex. http://tinyurl.com/3pqbts8
-Cory
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To post to this group, send email to diybio@googlegroups.com.
To unsubscribe from this group, send email to diybio+unsubscribe@googlegroups.com.
For more options, visit this group at http://groups.google.com/group/diybio?hl=en.
From: Cory Tobin <cory.tobin@gmail.com>
Date: Tue, Apr 5, 2011 at 2:18 AM
Subject: Re: gel electrophoresis resolution
To: diybio@googlegroups.com
I've never actually seen a gel quite like this one. The tailing of
the bands is usually due to loading too much DNA in the well. But the
bands don't look that bright. Maybe there actually is a lot of DNA
there but since the background light isn't being filtered out it just
doesn't appear very bright?
Some general gel troubleshooting:
- Make sure the the loading buffer is the same as the running buffer.
For example, if you used 1X TAE in the gel and you are using a 5X
loading buffer, the loading buffer should be made with 5X TAE so when
it's diluted in your sample the pH and salt concentration is the same
as 1X TAE.
- Load less DNA
- Replace the running buffer, assuming you have been reusing it
multiple times. Not as critical if you're using TBE.
- Use a lower voltage.
- Fill the chamber lower. 5mm over the top of the gel is ideal.
Excessive buffer leads to smearing.
For more gel debugging and optimization check out a pdf called "The
Sourcebook" by the company Cambrex. http://tinyurl.com/3pqbts8
-Cory
--
You received this message because you are subscribed to the Google Groups "DIYbio" group.
To post to this group, send email to diybio@googlegroups.com.
To unsubscribe from this group, send email to diybio+unsubscribe@googlegroups.com.
For more options, visit this group at http://groups.google.com/group/diybio?hl=en.
--
http://www.google.com/profiles/technologiclee
Monday, April 4, 2011
Saturday, April 2, 2011
Is That a Drum in Your Pants, or… No, That’s a Drum in Your Pants | Discoblog | Discover Magazine
Is That a Drum in Your Pants, or… No, That’s a Drum in Your Pants
Discoblog
Discover Magazine
Friday, April 1, 2011
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